Giroux was a reliable scorer for the Philadelphia Flyers and is among the franchise leaders in Stanley Cup Playoff points. And to think then-general manager Bobby Clarke forgot Giroux's name when announcing his selection with the No. 22 pick of the 2006 NHL Draft.

Clearly, Giroux has come a long way since then.

He was named the 19th captain in Flyers history Jan. 15, 2013, and became one of the best in the NHL on face-offs. Giroux won 58.0 percent of his draws in 2018-19, the eighth straight season he won at least 52 percent.

Giroux had 93 points (28 goals, 65 assists) in 2011-12, the most by a Flyers player since Eric Lindros had 93 in 1998-99. After being moved from center to left wing before the start of the 2017-18 season, he had 102 points (34 goals, 68 assists) in 82 games and finished second in the scoring race to Connor McDavid of the Edmonton Oilers (108). It was the most points in a season by a Philadelphia player since Lindros had 115 in 1995-96. Giroux was named an NHL Second-Team All-Star and finished fourth in voting for the Hart Trophy, awarded to the NHL's most valuable player.

A fan favorite, Giroux was on the cover of the EA Sports NHL 13 video game, and his No. 28 Flyers jersey was the top seller on the League website in 2011-12. He scored the deciding goal in a shootout April 11, 2010, the regular-season finale against the New York Rangers to send the Flyers to the playoffs. The Flyers reached the Cup Final that season, losing to the Chicago Blackhawks in six games despite Giroux's 21 points (10 goals, 11 assists) in 23 postseason games.

On April 13, 2012, Giroux set a Flyers playoff record with six points (three goals, three assists) against the Pittsburgh Penguins in Game 2 of the Eastern Conference First Round.

Giroux became the third Flyers representative to be named most valuable player of the NHL All-Star Game with three goals and an assist to help the Metropolitan Division win the 3-on-3 mini-tournament championship at the 2022 Honda NHL All-Star Game at T-Mobile Arena in Las Vegas, joining Reggie Leach (1980) and Wayne Simmonds (2017).

Giroux played his 1,000th NHL game, all for the Flyers, on March 17, 2022, a 5-4 win against the Nashville Predators at Wells Fargo Center, becoming the second player to reach the milestone with Philadelphia (Clarke; 1,144). Two days later, he was traded to the Florida Panthers for forward Owen Tippett, a first-round pick in the 2024 NHL Draft or 2025 NHL Draft, and a third-round pick in the 2023 NHL Draft after playing 15 NHL seasons for the Flyers, the past 10 as captain.

Giroux signed a three-year, $19.5 million contract with the Ottawa Senators on July 13, 2022, following the conclusion of an eight-year contract. The native of Hearst, Ontario, grew up in Ottawa and played his junior hockey with Gatineau of the Quebec Major Junior Hockey League, which is located just on the other side of the Ottawa River. He reached 1,001 points in the NHL with two goals and an assist in a 3-2 win against the Carolina Hurricanes on April 10, 2023.

On Dec. 9, 2023, Giroux had a goal and an assist in a 5-1 win at the Detroit Red Wings to give him 100 points in his 104th game with the Senators. He became the second-fastest player to reach the mark for Ottawa behind Dany Heatley (80 games).

At age 37, Giroux signed a one-year contract with the Senators on June 29, 2025. He had 50 points (15 goals, 35 assists) in 81 regular-season games and five points (one goal, four assists) in six playoff games, Ottawa's first postseason appearance since 2017.